Jacob Flores
Overview
Jacob Flores is a gap-year premedical sleep medicine fellow at Tricoastal Narcolepsy and Sleep Disorders Center. His passion toward scientific research and medicine led him toward Tricoastal, affording him the opportunity to learn and fulfill the synergistic connection between the two. His hope and aim in his journey toward becoming a physician is to lead and guide patients to thorough, efficient care. Jacob’s interest in medicine points toward preventing and managing the chronic conditions that increasingly and constantly affect people’s lives. As Jacob starts his medical journey in learning how to resolve such issues, his understanding of chronic debilitations will also start with sleep medicine. It is Jacob’s belief that just as our days start with sleep, great health should also start with great sleep.
Education
Jacob graduated summa cum laude with a BS in Biochemistry/Molecular Biology at Houston Christian University (Formerly named Houston Baptist University). He was also awarded outstanding student in Biochemistry and Molecular Biology of his graduating class. While attending college, Jacob was a research assistant at his home campus and enriched his experience in laboratories across the country during his summers. Post-Graduation, Jacob worked in a Pre-Physician Scientist training program at the Jackson Laboratory in Farmington, Connecticut where he interrogated genomic differences between individuals in chronic conditions such as diabetes. After concluding his term at the Jackson Laboratory, Jacob pursued to learn the ins and outs of patient care by becoming a medical assistant at a primary care clinic. His next goal is to attend medical school.
Employment
Gap year fellow, Tricoastal Narcolepsy and Sleep Disorders Center, April 2023-Present
Medical Assistant-Primary Care Clinic of Houston, October 2022-April 2023
MD/PhD Postbaccalaureate Research Fellow, The Jackson Laboratory- July 2020- July 2022
Summer Research Assistant, Iowa Carver College of Medicine Pre-MSTP program- Summer 2019
Summer Research Assistant, Boston University STaRS Program- Summer 2018
Undergraduate Research Assistant, August 2016- May 2020
Research and Publications
Lin J, Wang S, Audano PA, Meng D, Flores JI, Kosters W, Yang X, Jia P, Marschall T, Beck CR, Ye K. SVision: a deep learning approach to resolve complex structural variants. Nat Methods. 2022 Oct;19(10):1230-1233. doi: 10.1038/s41592-022-01609-w. Epub 2022 Sep 16. PMID: 36109679; PMCID: PMC9985066.
Balachandran P, Walawalkar IA, Flores JI, Dayton JN, Audano PA, Beck CR. Transposable element-mediated rearrangements are prevalent in human genomes. Nat Commun. 2022 Nov 19;13(1):7115. doi: 10.1038/s41467-022-34810-8. PMID: 36402840; PMCID: PMC9675761.
Ferraj A, Audano PA, Balachandran P, Czechanski A, Flores JI, Radecki AA, Mosur V, Gordon DS, Walawalkar IA, Eichler EE, Reinholdt LG, Beck CR. Resolution of structural variation in diverse mouse genomes reveals chromatin remodeling due to transposable elements. Cell Genom. 2023 Apr 5;3(5):100291. doi: 10.1016/j.xgen.2023.100291. PMID: 37228752; PMCID: PMC10203049.
Last updated: April 2024